The classification system devised by the Centers for Disease Control (USA) in 1987 for the reporting of HIV infection has been adopted for use in Australia. It comprises four mutually exclusive clinical groups. Persons classified in a particular group should not be reclassified in a preceding group if clinical findings resolve.

Group I — Acute illness

About 50% of patients have an acute illness associated with seroconversion. The illness usually occurs within 6 weeks of infection and is characterised by fever, night sweats, malaise, severe lethargy, anorexia, nausea, myalgia, arthralgia, headache, photophobia, sore throat, diarrhoea, lymphadenopathy, generalised maculoerythematous rash and thrombocytopaenia. Neurological manifestations including meningoencephalitis and peripheral neuritis may also be observed. Acute HIV infection should be considered in the differential diagnosis of glandular fever-like illnesses.

Chronic lethargy, depression and irritability may persist after the acute illness. Non-specific viraemic sequelae such as mucosal ulceration, desquamation, exacerbation of seborrhoea and recurrences of herpes simplex may occur.

*87/56/1*

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