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	<title>Pharmasweblog. Medical Weblog &#187; Pain Relief-Muscle Relaxers</title>
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	<description>This is a blog that is created to discuss all medical related issue, ranging from medical health, Anti-Smoking, Arthritis, Asthma and lot more</description>
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		<title>PAIN TREATMENT: SURGERY DIRECTED AT PERIPHERAL NERVES</title>
		<link>http://pharmasweblog.com/2011/06/pain-treatment-surgery-directed-at-peripheral-nerves/</link>
		<comments>http://pharmasweblog.com/2011/06/pain-treatment-surgery-directed-at-peripheral-nerves/#comments</comments>
		<pubDate>Sun, 12 Jun 2011 10:33:41 +0000</pubDate>
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				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>

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		<description><![CDATA[It is, of course, possible to inject local anaesthetics around peripheral nerves or around the sensory roots entering the spinal cord. These injections stop all nerve impulses travelling in that nerve and completely stop pain of peripheral origin. This highly satisfactory treatment can be used for only a day or so, however. The reason for [...]]]></description>
			<content:encoded><![CDATA[<p>It is, of course, possible to inject local anaesthetics around peripheral nerves or around the sensory roots entering the spinal cord. These injections stop all nerve impulses travelling in that nerve and completely stop pain of peripheral origin. This highly satisfactory treatment can be used for only a day or so, however. The reason for the time limit is that these drugs, which are all children and grandchildren of the herbal origin compound, cocaine, not only stop nerve impulses but also stop the transport of chemicals along fibres. This transport is necessary for feeding the nerve fibres, if it is stopped for more than a few days, the fibres die of starvation. Drugs may be invented which stop only the nerve impulses and these would be candidates for long-term trials.Cutting nerves can, of course, be done by surgery. It is done in some cancer patients who have only a short time to live. If they survive longer, the nerves regenerate, the pain returns and it is difficult to operate a second time. Noordenbros and I learned a salutary lesson in six cases who were astonishingly similar. All of them had partially cut across a nerve in the wrist, the median nerve, which supplies the thumb, neighbouring fingers and the palm of the hand. This nerve is often damaged in accidents, particularly if the hand breaks a window. All of these patients had felt desperate burning pain and tenderness in their useless hand for more than six months and were not helped by any treatments. Hand surgeons have become very skilled in grafting across gaps in nerves by deliberately suturing many strands of a fine nerve from elsewhere in the body to bridge the gap. The nerve fibres regenerate across the bridge and grow on to make contact with the distant structures. This delicate reconstructive surgery works very well if it is done soon after an accident which has torn a gap in a nerve.We persuaded the patients to allow the surgeons to cut out a length of the nerve where it had been damaged and to graft in new nerves so the nerve could reconstruct itself. The immediate effect of the operation was that the pain was completely gone but the hand was numb and paralyzed. Slowly, over six months, the nerves grew back and sensation and movement reappeared in the hand. The sad part of the story in that every patient developed precisely the pain state they had suffered before the operation. One patient killed himself in disappointment.The moral of the story is that you should not operate on peripheral nerves in this state. The pathology that was originally in the nerve had migrated centrally into the spinal cord, where angry nerve cells had become hyperexcitable and were the cause of the pain. Even cutting undamaged nerves or roots, while temporarily stopping the pain, can eventually set off a worse pain generated by central cells.There are, however, operations that are commonly done on peripheral nerves, ganglia or roots. One we have already described, to treat trigeminal neuralgia, involves destroying part of the sensory ganglion or root serving the face. Sometimes these patients suffer grim pains in their numb face, undoubtedly produced by the central migration of the effect of cutting nerves, as we have just described. However, the patient often has a pain-free period for months and years before the pain returns. Frankly, no one understands what is going on. Tiny lesions or gentle surgical manipulation of the ganglion or flooding the area around the ganglion with glycerol all produce long periods of relief. There are even successful cases reported in the literature where the operation was accidentally carried out on the wrong side of the face. All this is very mysterious and suggests some very fragile pathology. Needless to say, none of these many types of operation has ever been subjected to the rigorous test described at the beginning of this chapter.The plot thickens when we examine other types of pain-relieving surgery on limbs. A condition called Morton&#8217;s metatarsalgia is characterized by a small, very tender area on the sole of the foot. It is classically believed to be caused by the trapping of one of the fine nerves of the foot that dives down between the small long bones of the foot. The treatment is to dissect out the trapped nerve and cut it out. The Royal National Orthopaedic Hospital routinely examined the piece of tissue cut out and rarely found any nerve fibres at all! What is going on? Is it that the nerve is irrelevant but that there is some damaged tissue which reconstructs itself after surgery?Trapped nerves are a favourite explanation for pains with both patients and surgeons. It all sounds like good old-fashioned mechanical sense. &#8216;Trapped&#8217; nerves are regularly liberated by surgical dissection of various nerves in the arm, from the carpel tunnel in the wrist to nerves at the elbow and passing over the ribs. Results are variable and evidence for nerve damage is rare. There is no doubt that the surgery is disturbing tissue which is often inflamed but the reason for the results, if any, is a puzzle.Failure to cure pain by therapy directed at the periphery has naturally encouraged surgeons to move centrally. The first obvious target is the dorsal root ganglia, which nestle in their body hole between each vertebra. In the very common cases of back and neck pain with localized areas of tenderness, Skyrme Rees in Australia began an attempt to destroy nerves close to the vertebrae, and these operations have become common. Cuts were made in the region in an attempt to sever the nerves coming from the painful regions. After an initial period lasting some years, when the results were thought brilliant, the method fell into disrepute because of declining success and the obvious variability of which structures were cut.A much more controlled method was developed in Holland in which a thick needle was lowered with precise X-ray guidance to rest on one dorsal root ganglion. The needle contained electrical wires that allowed the tip to be heated to exactly 70°C (15 8 °F) to burn a small area around the tip. It was found that a considerable number of patients were relieved of their pain for fair periods of time. However, the apparent rationale for this treatment has now fallen into doubt. A Dutch team seeking to determine the best temperature for the treatment dropped the tip temperature to 40°C and achieved equally satisfactory results. The reason for the crisis is that this temperature is only tolerably warm and does not destroy tissue. I interpret the results as an inadvertant placebo trial which shows that the hot tip is not the effective component of the trial. The alternative possibilities are either that the effect is the consequence of placebo suggestion or that the presence of the needle without heat is the cause.The most major peripheral surgery for pain is the removal of a herniated disc, which pushes out from the soft cushion of tissue between the vertebrae. Some surgeons also carry out a bone graft to prevent movement of the vertebrae. This operation has been performed for more than seventy years and rose to great popularity, but doubts are increasing. The role of the protruding disc is not clear because the protrusion and the pain vary independently. A placebo trial of a treatment designed to dissolve the disc showed a very high rate of recovery after the injection of innocuous fluid under general anaesthesia. The supposed proof that the disc was cutting motor nerves and causing paralysis is now doubted because the pain can cause muscle wasting by central effects. The formerly enthusiastic proponents of the operation at the University of Miami have given it up in favour of a rigorous rehabilitation programme.Again, it is not at all clear if the beneficial results of the operation are due to suggestion or to some nonspecific disturbance of tissue in the region of the apparent origin of the pain.*56\219\2*</p>
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		<title>LOGICAL ANALYSIS OF POSTURE: SPEECH &amp; GAIT</title>
		<link>http://pharmasweblog.com/2011/01/logical-analysis-of-posture-speech-gait/</link>
		<comments>http://pharmasweblog.com/2011/01/logical-analysis-of-posture-speech-gait/#comments</comments>
		<pubDate>Mon, 24 Jan 2011 11:40:27 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>

		<guid isPermaLink="false">http://pharmasweblog.com/?p=164</guid>
		<description><![CDATA[Speech when taught is voluntarily controlled. The child or a student learning a new language learns to pronounce words and sentences using the lips, tongue, teeth, etc. After a while the whole process becomes automatic. The words are formed in the conscious brain but are executed by the subconscious brain. The movement of the speech [...]]]></description>
			<content:encoded><![CDATA[<p>Speech when taught is voluntarily controlled. The child or a student learning a new language learns to pronounce words and sentences using the lips, tongue, teeth, etc. After a while the whole process becomes automatic. The words are formed in the conscious brain but are executed by the subconscious brain. The movement of the speech apparatus (breath, vocal cords, tongue, lips etc) is subconsciously controlled. This is why most people who learn a second language speak with an &#8216;accent&#8217;. They have failed to retrain their brain to form new sounds like a native.<br />
Gait is also subconsciously controlled. If the conscious brain were to control and coordinate all the muscles involved in gait and balance, there would be frequent mistakes resulting in falls and injuries. This does not happen as Nature has entrusted the most advanced and precise part of the brain, the subconscious, to deal with it. The conscious mind is all too vulnerable to external influences and too engrossed with the thinking process to be able to control delicate and precise movements.<br />
*50\330\8*</p>
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		<title></title>
		<link>http://pharmasweblog.com/2011/01/162/</link>
		<comments>http://pharmasweblog.com/2011/01/162/#comments</comments>
		<pubDate>Tue, 18 Jan 2011 11:38:28 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>

		<guid isPermaLink="false">http://pharmasweblog.com/?p=162</guid>
		<description><![CDATA[HEADACHES THAT ARE NOT MIGRAINE: ALCOHOL, HOT-DOG AND ICE-CREAM HEADACHES Hot-dog headache Several people complain of headaches after eating cured meats of which hot-dog sausage is a classical example; others include bacon, ham, and salami. The headache comes on within half an hour of eating these foods and the offending substances are nitrites. These are [...]]]></description>
			<content:encoded><![CDATA[<p>HEADACHES THAT ARE NOT MIGRAINE: ALCOHOL, HOT-DOG AND ICE-CREAM HEADACHES</p>
<p>Hot-dog headache<br />
Several people complain of headaches after eating cured meats of which hot-dog sausage is a classical example; others include bacon, ham, and salami. The headache comes on within half an hour of eating these foods and the offending substances are nitrites. These are well known vasodilators, producing flushing of the face. Nitrites are added to the salt used in curing in order to give a uniform red colour to the meats.</p>
<p>Ice-cream headache<br />
This headache is caused by holding very cold substances such as ice or ice-cream in the mouth. The intense cooling of the roof of the mouth produces a pain which is then referred to the head.</p>
<p>Alcohol<br />
Alcohol is a powerful vasodilator, as evidenced by the flushed face of the inebriate. For this reason, it can produce a headache at the time of imbibition. But the term hangover is restricted to those symptoms, of which headache is predominant, which occur several hours later, usually the next day. It is almost certainly due to the breakdown products produced when alcohol is metabolized, including substances such as acetates and acetaldehyde.</p>
<p>*9/152/5*</p>
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		<title>MUSCLE PAIN</title>
		<link>http://pharmasweblog.com/2009/04/muscle-pain/</link>
		<comments>http://pharmasweblog.com/2009/04/muscle-pain/#comments</comments>
		<pubDate>Tue, 21 Apr 2009 04:55:13 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>
		<category><![CDATA[Pain Relief]]></category>

		<guid isPermaLink="false">http://pharmasweblog.com/2009/04/muscle-pain/</guid>
		<description><![CDATA[This probably accounts for more Australian health complaints than any other source of chronic pain. It affects literally millions who may wake up one morning and clutch at some tender area either in the neck or shoulders or in the lower back and continue to feel that spot for the rest of their lives. Back [...]]]></description>
			<content:encoded><![CDATA[<p><span style="font-family:Courier New; font-size:10pt">This probably accounts for more Australian health complaints than any other source of chronic pain. It affects literally millions who may wake up one morning and clutch at some tender area either in the neck or shoulders or in the lower back and continue to feel that spot for the rest of their lives.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">Back pain can be caused by abnormalities in the vertebral column which are present since birth. But they may also be produced by bad posture or by injuries such as whiplash.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">More often, they are associated with simple degenerative processes which occur in virtually everyone. For most of us, such changes are either without symptoms or cause no problem.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">But for many people the onset of degenerative processes is often associated with increased stresses and strains both at work and at home. This may lead to further weakening or the degeneration of the supporting structures of the vertebral column and can lead to disc problems.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">Lower back pain, occurring in the small of the back or in the muscles supporting the spine, is an extremely common complaint.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">To some extent this problem is caused by weakened muscles which can be helped by an appropriate exercise program. In fact, just being physically unfit can lead to lower back pain.<br />
</span></p>
<p><a href="http://www.d-store.net/?product=soma" title="buy soma Carisoprodol"><span style="font-family:Courier New; font-size:10pt">Everyday tensions which generate muscle spasms are another source.</span></a><span style="font-family:Courier New; font-size:10pt"> Lower back muscle spasms sometimes start with a strain or an injury to the region, such as lifting a heavy load with a bent back.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">They are then further aggravated by concern about the pain or by other stress conditions. These spasms are sometimes associated with very little X-ray evidence, making it difficult for doctors to find evidence that tension, or spasms, cause the pain. The spasms may in fact may not be present at the exact moment the doctor examines you.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">A full and complete history needs to be taken to ascertain stressful events which may be causing the tension in the muscles, which in turn is associated with the muscle pain.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">One of the major results of anxiety or stress is muscle tension, which occurs when muscles are contracted for overly long periods. The usual consequences of prolonged muscle activity include a buildup of toxic waste products within the muscle tissue.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">This in turn leads to pain which causes further spasms. Along with the build-up of waste products, there is a decreased availability of oxygen to the muscle tissue because of the relative decreased blood flow to the area.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">It is therefore easy to see that such situations lead to pain which can be continuous and difficult to treat without a multi-disciplinary approach.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">*71\37\8*<br />
</span></p>
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		<title>THE &#8216;REWARDS&#8217; OF PAIN: CHRONIC PAIN AND MARRIAGE DON&#8217;T MIX WELL</title>
		<link>http://pharmasweblog.com/2009/04/the-rewards-of-pain-chronic-pain-and-marriage-dont-mix-well/</link>
		<comments>http://pharmasweblog.com/2009/04/the-rewards-of-pain-chronic-pain-and-marriage-dont-mix-well/#comments</comments>
		<pubDate>Tue, 21 Apr 2009 04:52:37 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>
		<category><![CDATA[Pain Relief]]></category>

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		<description><![CDATA[Understandably, chronic pain and marriage don&#8217;t mix well. The divorce rate for chronic pain patients is remarkably high and is possibly related to the avoidance of sexual activity by many chronic pain sufferers.This, understandably, places relationships under great stress — particularly if there are existing problems. Pain is a great magnifier. Tolerance levels are already [...]]]></description>
			<content:encoded><![CDATA[<p><span style="font-family:Courier New; font-size:10pt">Understandably, chronic pain and marriage don&#8217;t mix well. The divorce rate for chronic pain patients is remarkably high and is possibly related to the avoidance of sexual activity by many chronic pain sufferers.This, understandably, places relationships under great stress — particularly if there are existing problems. Pain is a great magnifier. Tolerance levels are already low and the resulting emotional stress is greater than many relationships can stand. A breakup adds to the patient&#8217;s downward emotional spiral.<br />
</span></p>
<p><a href="http://www.drugstore-one.com/pain_relief.php" title="Pain Relief"><span style="font-family:Courier New; font-size:10pt">Some may be urged by well-meaning family or friends, or even the doctor, not to &#8216;overdo&#8217; it — which they sometimes carry out so zealously as to become so physically weakened that they have no choice but to take things easy!</span></a><span style="font-family:Courier New; font-size:10pt"> The traditional game, pointed out by Eric Beme in his excellent book The Games People Play, includes: &#8216;Try to cure me if you can!&#8217; This is very common among pain patients, who actually challenge the doctor to cure them. If patients have too often been encouraged to take things easy, it then becomes very difficult to convince them that physical activity may be increased without risking physical harm!<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">*48\37\8*<br />
</span></p>
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		<title>STRESS AND PAIN</title>
		<link>http://pharmasweblog.com/2009/04/stress-and-pain/</link>
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		<pubDate>Tue, 21 Apr 2009 04:49:42 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>
		<category><![CDATA[Pain Relief]]></category>

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		<description><![CDATA[Stress can lead to physical as well as psychological disturbances. These are most commonly treated by medication such as tranquillisers, muscle relaxants, sleeping pills, stimulants, antidepressants and mood-enhancers. Stress may be congenital, muscular, immunological, environmental — including accident and trauma situations — or infectious, neoplastic (associated with cancer),chemical, degenerative, emotional or psychological. Typical stress reactions [...]]]></description>
			<content:encoded><![CDATA[<p><span style="font-family:Courier New; font-size:10pt">Stress can lead to physical as well as psychological disturbances. These are most commonly treated by medication such as tranquillisers, muscle relaxants, sleeping pills, stimulants, antidepressants and mood-enhancers. Stress may be congenital, muscular, immunological, environmental — including accident and trauma situations — or infectious, neoplastic (associated with cancer),chemical, degenerative, emotional or psychological. Typical stress reactions are seen from preparing the body for fight, or for flight, such as changes in the heart&#8217;s output, blood pressure, and the movement or non-movement of the intestines. Anxiety is usually prominent. It can be treated with minor tranquillisers, or by explaining the cause of the pain and by reassuring the patient.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">Sleep disturbance is common. <a href="http://www.d-store.net/?product=soma" title="buy soma Carisoprodol">So are appetite changes and a decreased interest in sex.</a> These occur along with increased irritability, the withdrawal of interest and the weakening of relationships. There is also increased preoccupation with everything about the body.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">*26\37\8*<br />
</span></p>
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		<title>RSI — THE NEW EPIDEMIC</title>
		<link>http://pharmasweblog.com/2009/04/rsi-%e2%80%94-the-new-epidemic/</link>
		<comments>http://pharmasweblog.com/2009/04/rsi-%e2%80%94-the-new-epidemic/#comments</comments>
		<pubDate>Tue, 21 Apr 2009 04:46:43 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>
		<category><![CDATA[Pain Relief]]></category>

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		<description><![CDATA[Statistics are vague about the common chronic pain ailment — repetitive strain injury (RSI), which was so prevalent in Australia in the 1980&#8242;s that it was known as &#8216;kangaroo paw&#8217;. RSI is now the commonly used phrase used to describe a variety of soft tissue injuries or ailments. It is commonly seen in keyboard operators [...]]]></description>
			<content:encoded><![CDATA[<p><span style="font-family:Courier New; font-size:10pt">Statistics are vague about the common chronic pain ailment — repetitive strain injury (RSI), which was so prevalent in Australia in the 1980&#8242;s that it was known as &#8216;kangaroo paw&#8217;. RSI is now the commonly used phrase used to describe a variety of soft tissue injuries or ailments. It is commonly seen in keyboard operators and production workers, who develop painful hands, arms and, strangely, other areas of the body following repetitive tasks.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">It is a commonly held belief that RSI sprang upon an unsuspecting Australian public in the early 1980&#8242;s as a result of an industrial campaign by concerned unionists. <a href="http://www.drugstore-one.com/pain_relief.php" title="Pain Relief">In fact, RSI dates back to the Middle Ages when people in occupations such as spinning, cobbling and violin-making were said to be afflicted by painful hands and arms.<br />
</a></span></p>
<p><span style="font-family:Courier New; font-size:10pt">Other common conditions now brought under the umbrella of RSI include tenosynovitis, cervico-brachial syndrome, shoulder-hand syndrome and occupational overusage syndromes.<br />
</span></p>
<p><span style="font-family:Courier New; font-size:10pt">*4\37\8*<br />
</span></p>
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		<title>CAUSES OF HEADACHES: GLARE</title>
		<link>http://pharmasweblog.com/2009/03/causes-of-headaches-glare/</link>
		<comments>http://pharmasweblog.com/2009/03/causes-of-headaches-glare/#comments</comments>
		<pubDate>Wed, 11 Mar 2009 15:54:21 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Pain Relief-Muscle Relaxers]]></category>
		<category><![CDATA[Pain Relief]]></category>

		<guid isPermaLink="false">http://pharmasweblog.com/2009/03/causes-of-headaches-glare/</guid>
		<description><![CDATA[Too much light can cause just as many problems as too little light: too much light causes us to screw up our eyes tightly, causing muscle tension and headaches. What else could it be? Quite a number of conditions causing headache can also give eye symptoms. These have all been covered in other areas of [...]]]></description>
			<content:encoded><![CDATA[<p>Too much light can cause just as many problems as too little light: too much light causes us to screw up our eyes tightly, causing muscle tension and headaches.
</p>
<p>What else could it be?
</p>
<p>Quite a number of conditions causing headache can also give eye symptoms. These have all been covered in other areas of this book.
</p>
<p>Pain radiating from one eye can occur as a result of migraine or cluster headache.
</p>
<p>Herpes zoster, (shingles),&#8217;in a painful skin infection which can attack both the eye, and the skin of the forehead above the eye.
</p>
<p><a href="http://leadmedic.com/index.php?cPath=58" title="Pain Relief">Cervical spondylosis and arthritis of the neck can in certain circumstances cause severe spasm in the muscles of the neck, which creates pain that appears to radiate out of one eye.<br />
</a></p>
<p>Pain behind the eyes or just above the eyes in the forehead is often associated with muscle spasm in the neck, particularly the upper part of the neck. &#8216;Pension headaches caused in this way often cause eye pain.
</p>
<p>Although flashing lights in the eye tend to be associated with migraine, in pregnant women they can also be associated with pre-eclampsia.
</p>
<p>Blurred vision can be associated with focusing problems that require spectacles. It can also be a symptom of high blood pressure, acute glaucoma, and uraemia.
</p>
<p>A tumour of the pituitary gland can &#8216;pinch&#8217; the visual field to produce &#8216;tunnel vision&#8217;, in which there is loss of peripheral vision. Sometimes a brain tumour stops the patient seeing one sector of his visual field.
</p>
<p>Permanent blindness can occur in temporal arteritis and glaucoma (see above); and brain and pituitary tumours can each cause progressive blindness as a result of pressure on the nerves. Usually the loss of vision is progressive, but sometimes can be halted or reversed by prompt treatment. Temporary loss of vision with a headache is usually caused by migraine
</p>
<p>*81\20\2*</p>
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